MGMT O-6-methylguanine-DNA methyltransferase

Information
Symbol
MGMT
Type
protein-coding
Description
O-6-methylguanine-DNA methyltransferase
Entrez Gene ID
4255
Genome
hg19
Position
chr10:131,265,505-131,569,247
Genome
hg38
Position
chr10:129,467,241-129,770,983
MIM
156569 OMIM
HGNC
HGNC:7059 HGNC
Ensembl
ENSG00000170430 Ensembl
Links
NCBI Gene Cards OncoKB
Clinical Significance
MGeND ClinVar
Benign 0 2
Likely benign 0 10
not provided 0 2
Uncertain significance 0 40
Ranking
ClinVar
0
0
2
50
0
Frequency
EXAC_EAS
EXAC_EAS
HGVD
HGVD
TOMMO
TOMMO
Gene
Position
EXAC_EAS
EXAC_EAS
HGVD
HGVD
TOMMO
TOMMO
Gene
Position
Disease area statistics
[No Data.]
Locus Zoom
Variants
Search Word
Target data :
MGeND data only
Category :
Search word :
Filtering :
Variant name Gene AA change CDS Japanese
frequency		 TogoVar MGeND Genome ClinVar CIViC evidence DisGeNET entry COSMIC
occurrence		 Prediction
Entry Origin Type Annotation Entry Origin Annotation
Search Word
Target data :
MGeND data only
Category :
Search word :
Filtering :
Name MGeND Type Genome Size Chromosome Start Stop Ref Alt ClinVar Origin Entry CIViC evidence DisGeNET entry
Entry Origin Type Annotation
Search Word
Target data :
MGeND data only
Category :
Search word :
Filtering :
Name MGeND Type Genome Gene symbol Chromosome Genomic start Genomic stop Strand Ref Alt ClinVar Origin Entry CIViC evidence DisGeNET entry
Entry Origin Type Annotation
TypeID
MIM 156569 OMIM
HGNC HGNC:7059 HGNC
Ensembl ENSG00000170430 Ensembl
AllianceGenome HGNC:7059
DescrptionSourceLinks
IDGenomeChromosomeStartEndLength
ENST00000306010.8 hg38 chr10 129,467,190 129,767,519 300,330
ENST00000651593.1 hg38 chr10 129,467,241 129,770,983 303,743
ENST00000306010.8 hg19 chr10 131,265,454 131,565,783 300,330
ENST00000651593.1 hg19 chr10 131,265,505 131,569,247 303,743
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