Annotation Detail
Information
- Associated Genes
- MGMT
- Associated Variants
- MGMT OVEREXPRESSION
- Source Database
- MMMP
- Description
- O(6)-methylguanine DNA-methyltransferase (MGMT) overexpression in melanoma cells induces resistance to nitrosoureas and temozolomide but sensitizes to mitomycin-C
- MMMP State
- upregulated by
- MMMP Molecule
- MGMT
- MMMP Molecule Alias
- O-6-methylguanine-DNA methyltransferase
- MMMP Modifier
- MGMT genetic engineering
- MMMP Relationship
- resistance to
- MMMP Drug
- Carmustine
- MMMP Model
- 3
- MMMP Reference
- Passagne I, Toxicol Appl Pharmacol 2006, 211:97-105
- MMMP DNA/mRNA/Protein
- mRNA
Drugs
| Drug Name | Sensitivity | Supported |
|---|---|---|
| Carmustine | Resitance or Non-Reponse | true |