6-thioguanine
Information
- Drug Name
- 6-thioguanine
- Description
- Entry(CIViC)
CIViC
[No Data.]
Annotation
| Description | Associated Genes | Associated Variants | Sensitivity | Supported | Source | Links |
|---|---|---|---|---|---|---|
| Acquired resistance to 6-thioguanine in melanoma c... | MGMT | MGMT EXPRESSION | Resitance or Non-Reponse | true | MMMP | detail |
| NCT ID | Status | Phase | Summary | Start date | Completion date |
|---|---|---|---|---|---|
| NCT00504660 | Completed | Phase 2 | 6-TG, Capecitabine and Celecoxib Plus TMZ or CCNU for Anaplastic Glioma Patients | September 2003 | August 2010 |
| NCT00199069 | Completed | Phase 4 | German Multicenter Trial for Treatment of Newly Diagnosed Acute Lymphoblastic Leukemia in Adults (05/93) | April 1993 | May 2001 |
| NCT00587873 | Completed | Phase 2 | Sequential Administration of Oral 6-Thioguanine (6-TG) After Methotrexate (MTX) in Patients With Relapsed Hodgkin's Disease (Phase II) | March 1994 | June 2009 |
| NCT00588536 | Completed | Phase 2 | Study of Sequential Administration of Oral 6-Thioguanine After Methotrexate in Patients With LCH | January 1995 | June 2009 |
| NCT00176462 | Completed | Phase 2 | CINJALL: Treatment for Children With Acute Lymphocytic Leukemia | February 2001 | September 2008 |
| NCT00439296 | Terminated | Phase 1/Phase 2 | ABT-751 With Chemotherapy for Relapsed Pediatric ALL | May 22, 2006 | September 23, 2009 |
| NCT02141100 | Withdrawn | Phase 1/Phase 2 | Study of 6-Thioguanine in Combination With 6-Mercaptopurine During Maintenance Therapy of Childhood Lymphoma | July 2014 | October 2016 |