Annotation Detail

Information
Associated Genes
MGMT
Associated Variants
MGMT EXPRESSION
Source Database
MMMP
Description
Acquired resistance to 6-thioguanine in melanoma cells involves the repair enzyme O6-methylguanine-DNA methyltransferase (MGMT)
MMMP State
expressed
MMMP Molecule
MGMT
MMMP Molecule Alias
O-6-methylguanine-DNA methyltransferase
MMMP Modifier
MMMP Modifier Alias
MMMP Relationship
resistance to
MMMP Drug
6-thioguanine
MMMP Drug Alias
MMMP Model
3
MMMP Reference
Gefen N, Cancer Biol Ther 2010, 9:49-55
MMMP DNA/mRNA/Protein
protein
Drugs
Drug NameSensitivitySupported
6-thioguanineResitance or Non-Reponsetrue