Annotation Detail
Information
- Associated Genes
- DRD2
- Associated Variants
-
DRD2 p.His313= (p.H313=)
(
ENST00000544518.5,
ENST00000362072.8,
ENST00000538967.5,
ENST00000542968.5,
ENST00000346454.7 )
COMT p.Val158Met (p.V158M) ( ENST00000361682.11, ENST00000403184.5, ENST00000403710.5, ENST00000406520.7, ENST00000407537.5, ENST00000428707.2, ENST00000449653.5, ENST00000676678.1, ENST00000678255.1, ENST00000678769.1, ENST00000678868.1 )
DRD2 p.His313= (p.H313=) ( ENST00000346454.7, ENST00000362072.8, ENST00000538967.5, ENST00000542968.5, ENST00000544518.5 )
COMT p.Val158Met (p.V158M) ( ENST00000361682.11, ENST00000403184.5, ENST00000403710.5, ENST00000406520.7, ENST00000407537.5, ENST00000428707.2, ENST00000449653.5, ENST00000676678.1, ENST00000678255.1, ENST00000678769.1, ENST00000678868.1 ) - Associated Disease
- schizophrenia
- Source Database
- DisGeNET
- Description
- Multifactor-dimensionality reduction analysis suggested a two locus model (rs6275/DRD2 and rs4680/COMT) as the best model for gene-gene interaction with 90% cross-validation consistency and 42.42% prediction error in predicting disease risk among schizophrenia patients.
- Pubmed
- 19207030
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.291131657580184
- Year of publication
- 2009
Drugs