Annotation Detail

Information
Associated Genes
CCR5
Associated Variants
CCR5 MUTATION
CCR5 MUTATION
Associated Disease
osteomyelitis
Source Database
DisGeNET
Description
The CCR5Δ32 could be associated with protection against osteomyelitis caused by S. aureus, corroborating the data from Alonzo & Torres study, in which CCR5 receptor is required for S. aureus leukotoxin ED (LukED) cytotoxicity.
Pubmed
25638273
Section of the abstract supporting the evidence
CONCLUSION
Number of the section of the abstract supporting the evidence
5
Number of the sentence supporting the evidence
9
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.000271441872080303
Drugs