Annotation Detail

Information
Associated Genes
TNF
Associated Variants
rs1799964
NC_000006.12:g.31574699C>A
TNF c.-1037C>T
TNF c.-488G>A
NC_000006.12:g.31575324G>A
TNF c.186+123G>A ( ENST00000449264.3, ENST00000699334.1 )
rs1799964
NC_000006.12:g.31574699C>A
TNF c.-1037C>T
TNF c.-488G>A
NC_000006.12:g.31575324G>A
TNF c.186+123G>A ( ENST00000449264.3, ENST00000699334.1 )
Associated Disease
Malignant neoplasm of ovary
Source Database
DisGeNET
Description
We examined associations between six TNF single nucleotide polymorphisms (SNPs) (rs1799964, rs1800630, rs1799724, rs1800629, rs361525, rs1800610) and prostate cancer risk among 2,321 cases and 2,560 controls from two nested case-control studies within the Prostate, Lung, Colorectal, and Ovarian Cancer Screening Trial (PLCO, n = 2,561, 5 SNPs) and the Cancer Prevention Study II Nutrition Cohort (Nutrition Cohort, n = 2,320, 6 SNPs).
Pubmed
18196539
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.0124103812455733
Year of publication
2008
Drugs