chr4:55089802:C>T Detail (hg38) (KDR)
Information
Genome
Assembly | Position |
---|---|
hg19 | chr4:55,955,969-55,955,969 View the variant detail on this assembly version. |
hg38 | chr4:55,089,802-55,089,802 |
HGVS
Type | Transcript | Protein |
---|---|---|
RefSeq | NM_002253.2:c.3193G>A | NP_002244.1:p.Ala1065Thr |
Ensemble | ENST00000263923.5:c.3193G>A | ENST00000263923.5:p.Ala1065Thr |
Summary
MGeND
Clinical significance | |
Variant entry | |
GWAS entry | |
Disease area statistics | Show details |
Frequency
JP | HGVD:[No Data.] |
ToMMo:[No Data.] | |
NCBN:[No Data.] | |
NCBN(Hondo):[No Data.] | |
NCBN(Ryukyu):[No Data.] | |
East asia | ExAC:<0.001 |
Prediction
ClinVar
Clinical Significance | |
Review star | [No Data.] |
Show details |
Disease area statistics
[No Data.]
MGeND
[No Data.]
ClinVar
[No Data.]
CIViC
Disease | Drug | EL | ET | ED | CS | VO | TR | Pubmed | Links |
---|---|---|---|---|---|---|---|---|---|
angiosarcoma | Sunitinib,Sorafenib | D |
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Sensitivity/Response | Somatic | 3 | 19723655 | Detail |
DisGeNET
Score | Disease name | Description | Source | Pubmed | Links |
---|---|---|---|---|---|
0.004 | Non-small cell lung carcinoma | Likewise, activating mutations in the receptor tyrosine kinase KDR (VEGFR2) have... | BeFree | 25679062 | Detail |
0.121 | Hemangiosarcoma | Likewise, activating mutations in the receptor tyrosine kinase KDR (VEGFR2) have... | BeFree | 25679062 | Detail |
Annotation
Annotations
Descrption | Source | Links |
---|---|---|
COS-7 cells were transiently transfected with expression constructs encoding cDNAs for wild-type or ... | CIViC Evidence | Detail |
Likewise, activating mutations in the receptor tyrosine kinase KDR (VEGFR2) have been reported in an... | DisGeNET | Detail |
Likewise, activating mutations in the receptor tyrosine kinase KDR (VEGFR2) have been reported in an... | DisGeNET | Detail |
Overlapped Transcript Coordinates
Gene | Transcript ID | Exon Number | Chromosome | Start | Stop | Type | Amino Mutation | Transcript Position | Links |
---|
Overlapped Transcript
Gene | Transcript ID | Chromosome | Start | Stop | Links |
---|
- Gene
- -
- Genome
- hg38
- Position
- chr4:55,089,802-55,089,802
- Variant Type
- snv
- Reference Allele
- C
- Alternative Allele
- T
- East Asian Chromosome Counts (ExAC)
- 8646
- East Asian Allele Counts (ExAC)
- 0
- East Asian Heterozygous Counts (ExAC)
- 0
- East Asian Homozygous Counts (ExAC)
- 0
- East Asian Allele Frequency (ExAC)
- 0.0
- Chromosome Counts in All Race (ExAC)
- 121116
- Allele Counts in All Race (ExAC)
- 54
- Heterozygous Counts in All Race (ExAC)
- 54
- Homozygous Counts in All Race (ExAC)
- 0
- Allele Frequency in All Race (ExAC)
- 4.4585356187456653E-4
- Variant (CIViC) (CIViC Variant)
- A1065T
- Transcript 1 (CIViC Variant)
- ENST00000263923.4
- Variant URL (CIViC Variant)
- https://civic.genome.wustl.edu/links/variants/467
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