chr3:185793899:G>T Detail (hg38) (IGF2BP2)
Information
Genome
| Assembly | Position |
|---|---|
| hg19 | chr3:185,511,687-185,511,687 View the variant detail on this assembly version. |
| hg38 | chr3:185,793,899-185,793,899 |
HGVS
| Type | Transcript | Protein |
|---|---|---|
| RefSeq | NM_001007225.1:c.239+29254C>A | |
| NM_006548.4:c.239+29254C>A | ||
| NM_001291872.1:c.50+27113C>A |
Summary
MGeND
| Clinical significance | |
| Variant entry | |
| GWAS entry | |
| Disease area statistics | Show details |
Frequency
| JP | HGVD:[No Data.] |
| ToMMo:0.318 | |
| NCBN:[No Data.] | |
| NCBN(Hondo):[No Data.] | |
| NCBN(Ryukyu):[No Data.] | |
| East asia | ExAC:[No Data.] |
Prediction
ClinVar
| Clinical Significance |
risk factor
|
| Review star |  |
| Show details | |
Disease area statistics
[No Data.]
MGeND
[No Data.]
ClinVar
| Clinical significance | Last evaluated | Review status | Condition | Origin | Links |
|---|---|---|---|---|---|
|
risk factor
|
2007-06-01 | no assertion criteria provided | Diabetes mellitus type 2, susceptibility to |
germline
|
Detail |
CIViC
[No Data.]
DisGeNET
| Score | Disease name | Description | Source | Pubmed | Links |
|---|---|---|---|---|---|
| 0.012 | hyperglycemia | Polymorphisms in TCF7L2 (rs7903146, OR 1.10, 95% CI 1.04-1.17, p = 0.00097), FTO... | BeFree | 18853134 | Detail |
| 0.341 | Diabetes Mellitus, Non-Insulin-Dependent | Using MGA, some common gene variants were found to have little (<5%) but sign... | BeFree | 24993573 | Detail |
| 0.340 | Diabetes Mellitus, Non-Insulin-Dependent | Using MGA, some common gene variants were found to have little (<5%) but sign... | BeFree | 24993573 | Detail |
| 0.452 | Diabetes Mellitus, Non-Insulin-Dependent | Using MGA, some common gene variants were found to have little (<5%) but sign... | BeFree | 24993573 | Detail |
| 0.003 | hyperglycemia | Polymorphisms in TCF7L2 (rs7903146, OR 1.10, 95% CI 1.04-1.17, p = 0.00097), FTO... | BeFree | 18853134 | Detail |
| 0.003 | Diabetes Mellitus, Non-Insulin-Dependent | We analysed here the association between T2D (and related traits) and rs4402960 ... | BeFree | 20627640 | Detail |
| 0.452 | Diabetes Mellitus, Non-Insulin-Dependent | The IGF2BP2 gene rs1470579 and rs4402960 polymorphisms were associated with T2DM... | BeFree | 25247335 | Detail |
| 0.452 | Diabetes Mellitus, Non-Insulin-Dependent | The association of Insulin-like growth factor 2 mRNA-binding protein 2 (IGF2BP2)... | BeFree | 23029108 | Detail |
| 0.003 | Diabetes Mellitus, Non-Insulin-Dependent | We analysed here the association between T2D (and related traits) and rs4402960 ... | BeFree | 20627640 | Detail |
| 0.030 | obesity | Polymorphisms in TCF7L2 (rs7903146, OR 1.10, 95% CI 1.04-1.17, p = 0.00097), FTO... | BeFree | 18853134 | Detail |
| <0.001 | hyperglycemia | Polymorphisms in TCF7L2 (rs7903146, OR 1.10, 95% CI 1.04-1.17, p = 0.00097), FTO... | BeFree | 18853134 | Detail |
| 0.115 | Hypertensive disease | Genotype TT of SNP rs4402960 within the gene IGF2BP2 was associated with overwei... | BeFree | 24959828 | Detail |
| <0.001 | Overweight | Genotype TT of SNP rs4402960 within the gene IGF2BP2 was associated with overwei... | BeFree | 24959828 | Detail |
| <0.001 | Hypertensive disease | Genotype TT of SNP rs4402960 within the gene IGF2BP2 was associated with overwei... | BeFree | 24959828 | Detail |
| 0.003 | Overweight | Genotype TT of SNP rs4402960 within the gene IGF2BP2 was associated with overwei... | BeFree | 24959828 | Detail |
| 0.011 | obesity | We compared the genotype distribution of five genetic Single Nucleotide Polymorp... | BeFree | 25612568 | Detail |
| 0.393 | Diabetes Mellitus, Non-Insulin-Dependent | The risk associated with the presence of T2D was modified both by IGF2BP2_rs4402... | BeFree | 22419714 | Detail |
| 0.452 | Diabetes Mellitus, Non-Insulin-Dependent | The risk associated with the presence of T2D was modified both by IGF2BP2_rs4402... | BeFree | 22419714 | Detail |
| 0.129 | Metabolic syndrome X | Polymorphisms in TCF7L2 (rs7903146, OR 1.10, 95% CI 1.04-1.17, p = 0.00097), FTO... | BeFree | 18853134 | Detail |
| 0.322 | Diabetes Mellitus, Non-Insulin-Dependent | The analyses showed that age (P < 0.0001), BMI (P < 0.0001), and six varia... | BeFree | 20384434 | Detail |
| 0.452 | Diabetes Mellitus, Non-Insulin-Dependent | The analyses showed that age (P < 0.0001), BMI (P < 0.0001), and six varia... | BeFree | 20384434 | Detail |
| 0.010 | Impaired glucose tolerance | The analyses showed that age (P < 0.0001), BMI (P < 0.0001), and six varia... | BeFree | 20384434 | Detail |
| <0.001 | Impaired glucose tolerance | The analyses showed that age (P < 0.0001), BMI (P < 0.0001), and six varia... | BeFree | 20384434 | Detail |
| 0.002 | Diabetes | Meta-analysis indicated significant association between the IGF2BP2 rs4402960 an... | BeFree | 24898818 | Detail |
| 0.015 | diabetes mellitus | Meta-analysis indicated significant association between the IGF2BP2 rs4402960 an... | BeFree | 24898818 | Detail |
| 0.452 | Diabetes Mellitus, Non-Insulin-Dependent | The present study has replicated the association of IGF2BP2 rs4402960 with T2D i... | BeFree | 22770937 | Detail |
| 0.087 | Diabetes Mellitus, Non-Insulin-Dependent | Patients with schizophrenia have an increased prevalence of type 2 diabetes mell... | BeFree | 23656854 | Detail |
| <0.001 | Cardiovascular Diseases | In this study, we investigated the association of the rs7756992 of CDKAL1 and th... | BeFree | 24636221 | Detail |
| 0.452 | Diabetes Mellitus, Non-Insulin-Dependent | Replication of genome-wide association signals in UK samples reveals risk loci f... | GWASCAT | 17463249 | Detail |
| 0.452 | Diabetes Mellitus, Non-Insulin-Dependent | We found a lower risk of prediabetes and type 2 diabetes combined with coffee in... | BeFree | 25755232 | Detail |
| 0.452 | Diabetes Mellitus, Non-Insulin-Dependent | Confirmation of multiple risk Loci and genetic impacts by a genome-wide associat... | GWASCAT | 19401414 | Detail |
| <0.001 | Hypertensive disease | Contribution of CDKAL1 rs7756992 and IGF2BP2 rs4402960 polymorphisms in type 2 d... | BeFree | 24636221 | Detail |
| 0.421 | Diabetes Mellitus, Non-Insulin-Dependent | In this study, we investigated the association of the rs7756992 of CDKAL1 and th... | BeFree | 24636221 | Detail |
| 0.087 | Diabetes Mellitus, Non-Insulin-Dependent | The present study has replicated the association of IGF2BP2 rs4402960 with T2D i... | BeFree | 22770937 | Detail |
| 0.452 | Diabetes Mellitus, Non-Insulin-Dependent | Contribution of CDKAL1 rs7756992 and IGF2BP2 rs4402960 polymorphisms in type 2 d... | BeFree | 24636221 | Detail |
| 0.466 | Diabetes Mellitus, Non-Insulin-Dependent | We found a lower risk of prediabetes and type 2 diabetes combined with coffee in... | BeFree | 25755232 | Detail |
| <0.001 | Overweight | The present study confirms that the rs4402960 of IGF2BP2 gene is a strong candid... | BeFree | 24636221 | Detail |
| 0.011 | obesity | The present study confirms that the rs4402960 of IGF2BP2 gene is a strong candid... | BeFree | 24636221 | Detail |
| <0.001 | schizophrenia | Patients with schizophrenia have an increased prevalence of type 2 diabetes mell... | BeFree | 23656854 | Detail |
| <0.001 | prediabetes syndrome | We found a lower risk of prediabetes and type 2 diabetes combined with coffee in... | BeFree | 25755232 | Detail |
| 0.452 | Diabetes Mellitus, Non-Insulin-Dependent | Association between IGF2BP2 rs4402960 polymorphism and risk of type 2 diabetes m... | BeFree | 21839790 | Detail |
| 0.452 | Diabetes Mellitus, Non-Insulin-Dependent | According to our results, the case-control study and meta-analysis revealed a si... | BeFree | 24898818 | Detail |
| 0.452 | Diabetes Mellitus, Non-Insulin-Dependent | With collaborators (FUSION and WTCCC/UKT2D), we identified and confirmed three l... | GWASCAT | 17463246 | Detail |
| 0.452 | Diabetes Mellitus, Non-Insulin-Dependent | [The analyses showed that age (P < 0.0001), BMI (P < 0.0001), and six variants (... | GAD | 20384434 | Detail |
| 0.452 | Diabetes Mellitus, Non-Insulin-Dependent | [These results suggest that individuals with increased genetic susceptibility to... | GAD | 20203524 | Detail |
| 0.004 | Diabetes | Meta-analysis indicated significant association between the IGF2BP2 rs4402960 an... | BeFree | 24898818 | Detail |
| 0.452 | Diabetes Mellitus, Non-Insulin-Dependent | We identify T2D-associated variants in an intergenic region of chromosome 11p12,... | GWASCAT | 17463248 | Detail |
| <0.001 | Hypertensive disease | Contribution of CDKAL1 rs7756992 and IGF2BP2 rs4402960 polymorphisms in type 2 d... | BeFree | 24636221 | Detail |
| 0.374 | Diabetes Mellitus, Non-Insulin-Dependent | We replicated an association between rs4402960 and T2D status, and reported sign... | BeFree | 20627640 | Detail |
| 0.452 | Diabetes Mellitus, Non-Insulin-Dependent | Stratifying type 2 diabetes cases by BMI identifies genetic risk variants in LAM... | GWASCAT | 22693455 | Detail |
| 0.081 | prediabetes syndrome | We found that inverse associations between habitual coffee intake and the combin... | BeFree | 25755232 | Detail |
| 0.452 | Diabetes Mellitus, Non-Insulin-Dependent | NA | CLINVAR | Detail | |
| <0.001 | Cardiovascular Diseases | In this study, we investigated the association of the rs7756992 of CDKAL1 and th... | BeFree | 24636221 | Detail |
| 0.012 | diabetes mellitus | Meta-analysis indicated significant association between the IGF2BP2 rs4402960 an... | BeFree | 24898818 | Detail |
| <0.001 | prediabetes syndrome | We found that inverse associations between habitual coffee intake and the combin... | BeFree | 25755232 | Detail |
| 0.421 | Diabetes Mellitus, Non-Insulin-Dependent | We found a lower risk of prediabetes and type 2 diabetes combined with coffee in... | BeFree | 25755232 | Detail |
| 0.002 | Glucose Metabolism Disorders | [Our results suggest that combining genetic markers with traditional clinical ri... | GAD | 20384434 | Detail |
| 0.214 | Diabetes Mellitus, Insulin-Dependent | The present study has replicated the association of IGF2BP2 rs4402960 with T2D i... | BeFree | 22770937 | Detail |
| 0.452 | Diabetes Mellitus, Non-Insulin-Dependent | Meta-analysis of genome-wide association data and large-scale replication identi... | GWASCAT | 18372903 | Detail |
| 0.452 | Diabetes Mellitus, Non-Insulin-Dependent | Genome-wide trans-ancestry meta-analysis provides insight into the genetic archi... | GWASCAT | 24509480 | Detail |
| 0.340 | Diabetes Mellitus, Non-Insulin-Dependent | Eight SNPs in five loci were found to be associated with type 2 diabetes: rs3802... | BeFree | 18477659 | Detail |
| 0.214 | Diabetes Mellitus, Non-Insulin-Dependent | In Chinese Han, we replicated the associations between 7 genetic loci and T2D, w... | BeFree | 20509872 | Detail |
| 0.452 | Diabetes Mellitus, Non-Insulin-Dependent | Eight SNPs in five loci were found to be associated with type 2 diabetes: rs3802... | BeFree | 18477659 | Detail |
| 0.421 | Diabetes Mellitus, Non-Insulin-Dependent | In our case-control subjects, susceptibility to type 2 diabetes was replicated i... | BeFree | 19033397 | Detail |
| 0.393 | Diabetes Mellitus, Non-Insulin-Dependent | Seven SNPs in six genes known to increase the risk of T2DM in Caucasians were ge... | BeFree | 22569928 | Detail |
| 0.214 | Diabetes Mellitus, Non-Insulin-Dependent | Eight SNPs in five loci were found to be associated with type 2 diabetes: rs3802... | BeFree | 18477659 | Detail |
| 0.090 | Diabetes Mellitus, Non-Insulin-Dependent | In the present study, we aimed to validate the type 2 diabetes susceptibility al... | BeFree | 17827400 | Detail |
| 0.090 | Diabetes Mellitus, Non-Insulin-Dependent | In our case-control subjects, susceptibility to type 2 diabetes was replicated i... | BeFree | 19033397 | Detail |
| 0.214 | Diabetes Mellitus, Non-Insulin-Dependent | Seven SNPs in six genes known to increase the risk of T2DM in Caucasians were ge... | BeFree | 22569928 | Detail |
| 0.090 | Diabetes Mellitus, Non-Insulin-Dependent | Association to type 2 diabetes was found for rs13266634 (SLC30A8), rs7923837 (HH... | BeFree | 22923468 | Detail |
| 0.466 | Diabetes Mellitus, Non-Insulin-Dependent | Seven SNPs in six genes known to increase the risk of T2DM in Caucasians were ge... | BeFree | 22569928 | Detail |
| 0.340 | Diabetes Mellitus, Non-Insulin-Dependent | In Chinese Han, we replicated the associations between 7 genetic loci and T2D, w... | BeFree | 20509872 | Detail |
| 0.421 | Diabetes Mellitus, Non-Insulin-Dependent | Eight SNPs in five loci were found to be associated with type 2 diabetes: rs3802... | BeFree | 18477659 | Detail |
| 0.452 | Diabetes Mellitus, Non-Insulin-Dependent | In our case-control subjects, susceptibility to type 2 diabetes was replicated i... | BeFree | 19033397 | Detail |
| 0.090 | Diabetes Mellitus, Non-Insulin-Dependent | In Chinese Han, we replicated the associations between 7 genetic loci and T2D, w... | BeFree | 20509872 | Detail |
| 0.090 | Diabetes Mellitus, Non-Insulin-Dependent | Seven SNPs in six genes known to increase the risk of T2DM in Caucasians were ge... | BeFree | 22569928 | Detail |
| 0.214 | Diabetes Mellitus, Non-Insulin-Dependent | In the present study, we aimed to validate the type 2 diabetes susceptibility al... | BeFree | 17827400 | Detail |
| 0.042 | Diabetes Mellitus, Non-Insulin-Dependent | Association to type 2 diabetes was found for rs13266634 (SLC30A8), rs7923837 (HH... | BeFree | 22923468 | Detail |
| 0.341 | Diabetes Mellitus, Non-Insulin-Dependent | In Chinese Han, we replicated the associations between 7 genetic loci and T2D, w... | BeFree | 20509872 | Detail |
| 0.340 | Diabetes Mellitus, Non-Insulin-Dependent | Seven SNPs in six genes known to increase the risk of T2DM in Caucasians were ge... | BeFree | 22569928 | Detail |
| 0.452 | Diabetes Mellitus, Non-Insulin-Dependent | Seven SNPs in six genes known to increase the risk of T2DM in Caucasians were ge... | BeFree | 22569928 | Detail |
| 0.336 | Diabetes Mellitus, Non-Insulin-Dependent | Association to type 2 diabetes was found for rs13266634 (SLC30A8), rs7923837 (HH... | BeFree | 22923468 | Detail |
| 0.011 | Diabetes Mellitus, Non-Insulin-Dependent | In the present study, we aimed to validate the type 2 diabetes susceptibility al... | BeFree | 17827400 | Detail |
| 0.340 | Diabetes Mellitus, Non-Insulin-Dependent | In our case-control subjects, susceptibility to type 2 diabetes was replicated i... | BeFree | 19033397 | Detail |
| 0.421 | Diabetes Mellitus, Non-Insulin-Dependent | In Chinese Han, we replicated the associations between 7 genetic loci and T2D, w... | BeFree | 20509872 | Detail |
| 0.083 | Diabetes Mellitus, Non-Insulin-Dependent | Eight SNPs in five loci were found to be associated with type 2 diabetes: rs3802... | BeFree | 18477659 | Detail |
| 0.009 | gestational diabetes | 13 SNPs (FTO rs8050136, CDKAL1 rs7754840 and rs7756992, CDKN2A/2B rs10811661, HH... | BeFree | 22591707 | Detail |
| 0.336 | Diabetes Mellitus, Non-Insulin-Dependent | In Chinese Han, we replicated the associations between 7 genetic loci and T2D, w... | BeFree | 20509872 | Detail |
| 0.340 | Diabetes Mellitus, Non-Insulin-Dependent | Association to type 2 diabetes was found for rs13266634 (SLC30A8), rs7923837 (HH... | BeFree | 22923468 | Detail |
| 0.452 | Diabetes Mellitus, Non-Insulin-Dependent | In Chinese Han, we replicated the associations between 7 genetic loci and T2D, w... | BeFree | 20509872 | Detail |
| 0.452 | Diabetes Mellitus, Non-Insulin-Dependent | Association to type 2 diabetes was found for rs13266634 (SLC30A8), rs7923837 (HH... | BeFree | 22923468 | Detail |
| 0.005 | gestational diabetes | The minor alleles of rs7903146 (TCF7L2), rs12255372 (TCF7L2), rs1799884 (-30G/A,... | BeFree | 23690305 | Detail |
| 0.024 | gestational diabetes | We also found that the risk alleles of rs2383208 (b = -0.085, p = 0.003), rs4402... | BeFree | 22096510 | Detail |
| 0.123 | gestational diabetes | The minor alleles of rs7903146 (TCF7L2), rs12255372 (TCF7L2), rs1799884 (-30G/A,... | BeFree | 23690305 | Detail |
| 0.002 | gestational diabetes | The minor alleles of rs7903146 (TCF7L2), rs12255372 (TCF7L2), rs1799884 (-30G/A,... | BeFree | 23690305 | Detail |
| 0.009 | gestational diabetes | The minor alleles of rs7903146 (TCF7L2), rs12255372 (TCF7L2), rs1799884 (-30G/A,... | BeFree | 23690305 | Detail |
| 0.126 | gestational diabetes | The minor alleles of rs7903146 (TCF7L2), rs12255372 (TCF7L2), rs1799884 (-30G/A,... | BeFree | 23690305 | Detail |
| 0.145 | gestational diabetes | The minor alleles of rs7903146 (TCF7L2), rs12255372 (TCF7L2), rs1799884 (-30G/A,... | BeFree | 23690305 | Detail |
| 0.421 | Diabetes Mellitus, Non-Insulin-Dependent | Five risk variants in IGF2BP2 (rs4402960, rs1470579), CDKAL1 (rs10946398), SLC30... | BeFree | 24736664 | Detail |
| 0.452 | Diabetes Mellitus, Non-Insulin-Dependent | Five risk variants in IGF2BP2 (rs4402960, rs1470579), CDKAL1 (rs10946398), SLC30... | BeFree | 24736664 | Detail |
| 0.214 | Diabetes Mellitus, Non-Insulin-Dependent | Five risk variants in IGF2BP2 (rs4402960, rs1470579), CDKAL1 (rs10946398), SLC30... | BeFree | 24736664 | Detail |
| 0.006 | obesity | In this study, we asked whether the co-occurrence of risk alleles in or near fiv... | BeFree | 24062323 | Detail |
| 0.003 | Impaired glucose tolerance | In this study, we asked whether the co-occurrence of risk alleles in or near fiv... | BeFree | 24062323 | Detail |
| 0.214 | Diabetes Mellitus, Non-Insulin-Dependent | In this study, we asked whether the co-occurrence of risk alleles in or near fiv... | BeFree | 24062323 | Detail |
| 0.011 | obesity | In this study, we asked whether the co-occurrence of risk alleles in or near fiv... | BeFree | 24062323 | Detail |
| 0.329 | Diabetes Mellitus, Non-Insulin-Dependent | In this study, we asked whether the co-occurrence of risk alleles in or near fiv... | BeFree | 24062323 | Detail |
| 0.007 | Impaired glucose tolerance | In this study, we asked whether the co-occurrence of risk alleles in or near fiv... | BeFree | 24062323 | Detail |
Annotation
Annotations
| Descrption | Source | Links |
|---|---|---|
| NM_006548.6(IGF2BP2):c.239+29254C>A AND Diabetes mellitus type 2, susceptibility to | ClinVar | Detail |
| Polymorphisms in TCF7L2 (rs7903146, OR 1.10, 95% CI 1.04-1.17, p = 0.00097), FTO (rs9939609, OR 1.08... | DisGeNET | Detail |
| Using MGA, some common gene variants were found to have little (<5%) but significant impact on th... | DisGeNET | Detail |
| Using MGA, some common gene variants were found to have little (<5%) but significant impact on th... | DisGeNET | Detail |
| Using MGA, some common gene variants were found to have little (<5%) but significant impact on th... | DisGeNET | Detail |
| Polymorphisms in TCF7L2 (rs7903146, OR 1.10, 95% CI 1.04-1.17, p = 0.00097), FTO (rs9939609, OR 1.08... | DisGeNET | Detail |
| We analysed here the association between T2D (and related traits) and rs4402960 and rs1470579 in IGF... | DisGeNET | Detail |
| The IGF2BP2 gene rs1470579 and rs4402960 polymorphisms were associated with T2DM and therapeutic eff... | DisGeNET | Detail |
| The association of Insulin-like growth factor 2 mRNA-binding protein 2 (IGF2BP2) common variants (rs... | DisGeNET | Detail |
| We analysed here the association between T2D (and related traits) and rs4402960 and rs1470579 in IGF... | DisGeNET | Detail |
| Polymorphisms in TCF7L2 (rs7903146, OR 1.10, 95% CI 1.04-1.17, p = 0.00097), FTO (rs9939609, OR 1.08... | DisGeNET | Detail |
| Polymorphisms in TCF7L2 (rs7903146, OR 1.10, 95% CI 1.04-1.17, p = 0.00097), FTO (rs9939609, OR 1.08... | DisGeNET | Detail |
| Genotype TT of SNP rs4402960 within the gene IGF2BP2 was associated with overweight (odds ratio (OR)... | DisGeNET | Detail |
| Genotype TT of SNP rs4402960 within the gene IGF2BP2 was associated with overweight (odds ratio (OR)... | DisGeNET | Detail |
| Genotype TT of SNP rs4402960 within the gene IGF2BP2 was associated with overweight (odds ratio (OR)... | DisGeNET | Detail |
| Genotype TT of SNP rs4402960 within the gene IGF2BP2 was associated with overweight (odds ratio (OR)... | DisGeNET | Detail |
| We compared the genotype distribution of five genetic Single Nucleotide Polymorphisms (SNPs) known t... | DisGeNET | Detail |
| The risk associated with the presence of T2D was modified both by IGF2BP2_rs4402960 and PPARγ_rs1801... | DisGeNET | Detail |
| The risk associated with the presence of T2D was modified both by IGF2BP2_rs4402960 and PPARγ_rs1801... | DisGeNET | Detail |
| Polymorphisms in TCF7L2 (rs7903146, OR 1.10, 95% CI 1.04-1.17, p = 0.00097), FTO (rs9939609, OR 1.08... | DisGeNET | Detail |
| The analyses showed that age (P < 0.0001), BMI (P < 0.0001), and six variants (IGF2BP2 rs44029... | DisGeNET | Detail |
| The analyses showed that age (P < 0.0001), BMI (P < 0.0001), and six variants (IGF2BP2 rs44029... | DisGeNET | Detail |
| The analyses showed that age (P < 0.0001), BMI (P < 0.0001), and six variants (IGF2BP2 rs44029... | DisGeNET | Detail |
| The analyses showed that age (P < 0.0001), BMI (P < 0.0001), and six variants (IGF2BP2 rs44029... | DisGeNET | Detail |
| Meta-analysis indicated significant association between the IGF2BP2 rs4402960 and CDKAL1 rs7756992 p... | DisGeNET | Detail |
| Meta-analysis indicated significant association between the IGF2BP2 rs4402960 and CDKAL1 rs7756992 p... | DisGeNET | Detail |
| The present study has replicated the association of IGF2BP2 rs4402960 with T2D in the Czech populati... | DisGeNET | Detail |
| Patients with schizophrenia have an increased prevalence of type 2 diabetes mellitus, and type 2 dia... | DisGeNET | Detail |
| In this study, we investigated the association of the rs7756992 of CDKAL1 and the rs4402960 of IGF2B... | DisGeNET | Detail |
| Replication of genome-wide association signals in UK samples reveals risk loci for type 2 diabetes. | DisGeNET | Detail |
| We found a lower risk of prediabetes and type 2 diabetes combined with coffee intake among individua... | DisGeNET | Detail |
| Confirmation of multiple risk Loci and genetic impacts by a genome-wide association study of type 2 ... | DisGeNET | Detail |
| Contribution of CDKAL1 rs7756992 and IGF2BP2 rs4402960 polymorphisms in type 2 diabetes, diabetic co... | DisGeNET | Detail |
| In this study, we investigated the association of the rs7756992 of CDKAL1 and the rs4402960 of IGF2B... | DisGeNET | Detail |
| The present study has replicated the association of IGF2BP2 rs4402960 with T2D in the Czech populati... | DisGeNET | Detail |
| Contribution of CDKAL1 rs7756992 and IGF2BP2 rs4402960 polymorphisms in type 2 diabetes, diabetic co... | DisGeNET | Detail |
| We found a lower risk of prediabetes and type 2 diabetes combined with coffee intake among individua... | DisGeNET | Detail |
| The present study confirms that the rs4402960 of IGF2BP2 gene is a strong candidate for Type 2 diabe... | DisGeNET | Detail |
| The present study confirms that the rs4402960 of IGF2BP2 gene is a strong candidate for Type 2 diabe... | DisGeNET | Detail |
| Patients with schizophrenia have an increased prevalence of type 2 diabetes mellitus, and type 2 dia... | DisGeNET | Detail |
| We found a lower risk of prediabetes and type 2 diabetes combined with coffee intake among individua... | DisGeNET | Detail |
| Association between IGF2BP2 rs4402960 polymorphism and risk of type 2 diabetes mellitus: a meta-anal... | DisGeNET | Detail |
| According to our results, the case-control study and meta-analysis revealed a significant associatio... | DisGeNET | Detail |
| With collaborators (FUSION and WTCCC/UKT2D), we identified and confirmed three loci associated with ... | DisGeNET | Detail |
| [The analyses showed that age (P < 0.0001), BMI (P < 0.0001), and six variants (IGF2BP2 rs4402960, P... | DisGeNET | Detail |
| [These results suggest that individuals with increased genetic susceptibility to T2D have decreased ... | DisGeNET | Detail |
| Meta-analysis indicated significant association between the IGF2BP2 rs4402960 and CDKAL1 rs7756992 p... | DisGeNET | Detail |
| We identify T2D-associated variants in an intergenic region of chromosome 11p12, contribute to the i... | DisGeNET | Detail |
| Contribution of CDKAL1 rs7756992 and IGF2BP2 rs4402960 polymorphisms in type 2 diabetes, diabetic co... | DisGeNET | Detail |
| We replicated an association between rs4402960 and T2D status, and reported significant associations... | DisGeNET | Detail |
| Stratifying type 2 diabetes cases by BMI identifies genetic risk variants in LAMA1 and enrichment fo... | DisGeNET | Detail |
| We found that inverse associations between habitual coffee intake and the combined risk of type 2 di... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| In this study, we investigated the association of the rs7756992 of CDKAL1 and the rs4402960 of IGF2B... | DisGeNET | Detail |
| Meta-analysis indicated significant association between the IGF2BP2 rs4402960 and CDKAL1 rs7756992 p... | DisGeNET | Detail |
| We found that inverse associations between habitual coffee intake and the combined risk of type 2 di... | DisGeNET | Detail |
| We found a lower risk of prediabetes and type 2 diabetes combined with coffee intake among individua... | DisGeNET | Detail |
| [Our results suggest that combining genetic markers with traditional clinical risk factors has the p... | DisGeNET | Detail |
| The present study has replicated the association of IGF2BP2 rs4402960 with T2D in the Czech populati... | DisGeNET | Detail |
| Meta-analysis of genome-wide association data and large-scale replication identifies additional susc... | DisGeNET | Detail |
| Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 di... | DisGeNET | Detail |
| Eight SNPs in five loci were found to be associated with type 2 diabetes: rs3802177 [odds ratio (OR)... | DisGeNET | Detail |
| In Chinese Han, we replicated the associations between 7 genetic loci and T2D, with risk allele-spec... | DisGeNET | Detail |
| Eight SNPs in five loci were found to be associated with type 2 diabetes: rs3802177 [odds ratio (OR)... | DisGeNET | Detail |
| In our case-control subjects, susceptibility to type 2 diabetes was replicated in TCF7L2 (rs12255372... | DisGeNET | Detail |
| Seven SNPs in six genes known to increase the risk of T2DM in Caucasians were genotyped by means of ... | DisGeNET | Detail |
| Eight SNPs in five loci were found to be associated with type 2 diabetes: rs3802177 [odds ratio (OR)... | DisGeNET | Detail |
| In the present study, we aimed to validate the type 2 diabetes susceptibility alleles identified in ... | DisGeNET | Detail |
| In our case-control subjects, susceptibility to type 2 diabetes was replicated in TCF7L2 (rs12255372... | DisGeNET | Detail |
| Seven SNPs in six genes known to increase the risk of T2DM in Caucasians were genotyped by means of ... | DisGeNET | Detail |
| Association to type 2 diabetes was found for rs13266634 (SLC30A8), rs7923837 (HHEX), rs10811661 (CDK... | DisGeNET | Detail |
| Seven SNPs in six genes known to increase the risk of T2DM in Caucasians were genotyped by means of ... | DisGeNET | Detail |
| In Chinese Han, we replicated the associations between 7 genetic loci and T2D, with risk allele-spec... | DisGeNET | Detail |
| Eight SNPs in five loci were found to be associated with type 2 diabetes: rs3802177 [odds ratio (OR)... | DisGeNET | Detail |
| In our case-control subjects, susceptibility to type 2 diabetes was replicated in TCF7L2 (rs12255372... | DisGeNET | Detail |
| In Chinese Han, we replicated the associations between 7 genetic loci and T2D, with risk allele-spec... | DisGeNET | Detail |
| Seven SNPs in six genes known to increase the risk of T2DM in Caucasians were genotyped by means of ... | DisGeNET | Detail |
| In the present study, we aimed to validate the type 2 diabetes susceptibility alleles identified in ... | DisGeNET | Detail |
| Association to type 2 diabetes was found for rs13266634 (SLC30A8), rs7923837 (HHEX), rs10811661 (CDK... | DisGeNET | Detail |
| In Chinese Han, we replicated the associations between 7 genetic loci and T2D, with risk allele-spec... | DisGeNET | Detail |
| Seven SNPs in six genes known to increase the risk of T2DM in Caucasians were genotyped by means of ... | DisGeNET | Detail |
| Seven SNPs in six genes known to increase the risk of T2DM in Caucasians were genotyped by means of ... | DisGeNET | Detail |
| Association to type 2 diabetes was found for rs13266634 (SLC30A8), rs7923837 (HHEX), rs10811661 (CDK... | DisGeNET | Detail |
| In the present study, we aimed to validate the type 2 diabetes susceptibility alleles identified in ... | DisGeNET | Detail |
| In our case-control subjects, susceptibility to type 2 diabetes was replicated in TCF7L2 (rs12255372... | DisGeNET | Detail |
| In Chinese Han, we replicated the associations between 7 genetic loci and T2D, with risk allele-spec... | DisGeNET | Detail |
| Eight SNPs in five loci were found to be associated with type 2 diabetes: rs3802177 [odds ratio (OR)... | DisGeNET | Detail |
| 13 SNPs (FTO rs8050136, CDKAL1 rs7754840 and rs7756992, CDKN2A/2B rs10811661, HHEX rs1111875, IGF2BP... | DisGeNET | Detail |
| In Chinese Han, we replicated the associations between 7 genetic loci and T2D, with risk allele-spec... | DisGeNET | Detail |
| Association to type 2 diabetes was found for rs13266634 (SLC30A8), rs7923837 (HHEX), rs10811661 (CDK... | DisGeNET | Detail |
| In Chinese Han, we replicated the associations between 7 genetic loci and T2D, with risk allele-spec... | DisGeNET | Detail |
| Association to type 2 diabetes was found for rs13266634 (SLC30A8), rs7923837 (HHEX), rs10811661 (CDK... | DisGeNET | Detail |
| The minor alleles of rs7903146 (TCF7L2), rs12255372 (TCF7L2), rs1799884 (-30G/A, GCK), rs5219 (E23K,... | DisGeNET | Detail |
| We also found that the risk alleles of rs2383208 (b = -0.085, p = 0.003), rs4402960 (b = -0.057, p =... | DisGeNET | Detail |
| The minor alleles of rs7903146 (TCF7L2), rs12255372 (TCF7L2), rs1799884 (-30G/A, GCK), rs5219 (E23K,... | DisGeNET | Detail |
| The minor alleles of rs7903146 (TCF7L2), rs12255372 (TCF7L2), rs1799884 (-30G/A, GCK), rs5219 (E23K,... | DisGeNET | Detail |
| The minor alleles of rs7903146 (TCF7L2), rs12255372 (TCF7L2), rs1799884 (-30G/A, GCK), rs5219 (E23K,... | DisGeNET | Detail |
| The minor alleles of rs7903146 (TCF7L2), rs12255372 (TCF7L2), rs1799884 (-30G/A, GCK), rs5219 (E23K,... | DisGeNET | Detail |
| The minor alleles of rs7903146 (TCF7L2), rs12255372 (TCF7L2), rs1799884 (-30G/A, GCK), rs5219 (E23K,... | DisGeNET | Detail |
| Five risk variants in IGF2BP2 (rs4402960, rs1470579), CDKAL1 (rs10946398), SLC30A8 (rs13266634), and... | DisGeNET | Detail |
| Five risk variants in IGF2BP2 (rs4402960, rs1470579), CDKAL1 (rs10946398), SLC30A8 (rs13266634), and... | DisGeNET | Detail |
| Five risk variants in IGF2BP2 (rs4402960, rs1470579), CDKAL1 (rs10946398), SLC30A8 (rs13266634), and... | DisGeNET | Detail |
| In this study, we asked whether the co-occurrence of risk alleles in or near five genes modulating i... | DisGeNET | Detail |
| In this study, we asked whether the co-occurrence of risk alleles in or near five genes modulating i... | DisGeNET | Detail |
| In this study, we asked whether the co-occurrence of risk alleles in or near five genes modulating i... | DisGeNET | Detail |
| In this study, we asked whether the co-occurrence of risk alleles in or near five genes modulating i... | DisGeNET | Detail |
| In this study, we asked whether the co-occurrence of risk alleles in or near five genes modulating i... | DisGeNET | Detail |
| In this study, we asked whether the co-occurrence of risk alleles in or near five genes modulating i... | DisGeNET | Detail |
Overlapped Transcript
| Gene | Transcript ID | Chromosome | Start | Stop | Links |
|---|
- Gene
- -
- dbSNP
- rs4402960 dbSNP
- Genome
- hg38
- Position
- chr3:185,793,899-185,793,899
- Variant Type
- snv
- Reference Allele
- G
- Alternative Allele
- T
- ToMMo VCF FILTER column value (ToMMo 8.3KJPN Allele Frequency Panel(v20200831))
- PASS
- Total VCF ID column value (ToMMo 8.3KJPN Allele Frequency Panel(v20200831))
- rs4402960
- Allele frequency, for each ALT allele (ToMMo 8.3KJPN Allele Frequency Panel(v20200831))
- 0.3183
- Allele count in genotypes, for each ALT allele (ToMMo 8.3KJPN Allele Frequency Panel(v20200831))
- 5334
- Total number of alleles in called genotypes (ToMMo 8.3KJPN Allele Frequency Panel(v20200831))
- 16760
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