chr20:41028818:> Detail (hg38) (TOP1)
Information
Genome
| Assembly | Position |
|---|---|
| hg19 | chr20:39,657,458-39,753,127 |
| hg38 | chr20:41,028,818-41,124,487 |
HGVS
| Type | Transcript | Protein |
|---|---|---|
Summary
MGeND
| Clinical significance | |
| Variant entry | |
| GWAS entry | |
| Disease area statistics | Show details |
Frequency
[No Data.]
Prediction
[No Data.]
ClinVar
| Clinical Significance | |
| Review star | [No Data.] |
| Show details | |
Links
Disease area statistics
[No Data.]
MGeND
[No Data.]
ClinVar
[No Data.]
CIViC
| Disease | Drug | EL | ET | ED | CS | VO | TR | Pubmed | Links |
|---|---|---|---|---|---|---|---|---|---|
| ovarian cancer | Topotecan,Cyclophosphamide,Carboplatin | B |
Predictive
|
Supports
|
Sensitivity/Response |
N/A
|
2 | 19648970 | Detail |
| colorectal cancer | Irinotecan | B |
Predictive
|
Supports
|
Sensitivity/Response |
N/A
|
3 | 19775480 | Detail |
DisGeNET
[No Data.]
Annotation
Annotations
| Descrption | Source | Links |
|---|---|---|
| Shorter progression free survival was observed in patients with low expression (IHC) of topoisomeras... | CIViC Evidence | Detail |
| 498 patients were retrospectively analyzed for topoisomerase 1 expression (IHC). In the subgroup of ... | CIViC Evidence | Detail |
Overlapped Transcript Coordinates
| Gene | Transcript ID | Exon Number | Chromosome | Start | Stop | Type | Amino Mutation | Transcript Position | Links |
|---|
Overlapped Transcript
| Gene | Transcript ID | Chromosome | Start | Stop | Links |
|---|
- Gene
- -
- Genome
- hg38
- Position
- chr20:41,028,818-41,124,487
- Variant Type
- snv
- Variant (CIViC) (CIViC Variant)
- EXPRESSION
- Transcript 1 (CIViC Variant)
- ENST00000361337.2
- Variant URL (CIViC Variant)
- https://civic.genome.wustl.edu/links/variants/384
Genome browser