chr12:56473645:> Detail (hg19) (ERBB3)

Information

Genome

Assembly Position
hg19 chr12:56,473,645-56,497,289
hg38 chr12:56,079,861-56,103,505 

HGVS

Type Transcript Protein
Summary

MGeND

Clinical significance
Variant entry
GWAS entry
Disease area statistics Show details

Frequency

[No Data.]

Prediction

[No Data.]

ClinVar

Clinical Significance
Review star [No Data.]
Show details
Links
Disease area statistics
[No Data.]
MGeND
[No Data.]
ClinVar
[No Data.]
CIViC
Disease Drug EL ET ED CS VO TR Pubmed Links
cancer Anti-ErbB3 Monoclonal Antibody AV-203 D Predictive Does Not Support Sensitivity/Response N/A 3 25542901 Detail
pancreatic ductal adenocarcinoma Pertuzumab,9F7-F11 D Predictive Supports Sensitivity/Response N/A 3 25216528 Detail
DisGeNET
[No Data.]
Annotation

Annotations

DescrptionSourceLinks
The authors conducted an in vivo efficacy study of AV-203 (ERBB3 inhibitory antibody) using a panel ... CIViC Evidence Detail
In mice xenografts expressing ERBB3 (HER3) the combination of ERBB2 (HER2) and ERBB3 inhibitors pert... CIViC Evidence Detail

Overlapped Transcript Coordinates

Gene Transcript ID Exon Number Chromosome Start Stop Type Amino Mutation Transcript Position Links

Overlapped Transcript

Gene Transcript ID Chromosome Start Stop Links
Gene
-
Genome
hg19
Position
chr12:56,473,645-56,497,289
Variant Type
snv
Variant (CIViC) (CIViC Variant)
EXPRESSION
Transcript 1 (CIViC Variant)
ENST00000267101.3
Variant URL (CIViC Variant)
https://civic.genome.wustl.edu/links/variants/361
Genome browser