Tyrphostin AG 1296
Information
- Drug Name
- Tyrphostin AG 1296
- Description
- Entry(CIViC)
- 2
CIViC
| Disease | Mutation | EL | ET | ED | CS | VO | TR | Pubmed | Links |
|---|---|---|---|---|---|---|---|---|---|
| acute myeloid leukemia | FLT3 ITD FLT3 ITD | D |
Predictive
|
Supports
|
Sensitivity/Response | Somatic | 4 | 12357354 | Detail |
| acute myeloid leukemia |
FLT3 p.Asp835Val (p.D835V) ( ENST00000241453.12 ) FLT3 p.Asp835Val (p.D835V) ( ENST00000241453.12 ) |
D |
Predictive
|
Supports
|
Sensitivity/Response | Somatic | 3 | 17330097 | Detail |
Annotation
| Description | Associated Genes | Associated Variants | Sensitivity | Supported | Source | Links |
|---|---|---|---|---|---|---|
| AG1296 is effective in triggering apoptosis in Ba/... | FLT3 | FLT3 ITD FLT3 ITD | Sensitivity | true | CIViC Evidence | detail |
| Murine Ba/F3 cells with FLT3 D835V mutation were a... | FLT3 |
FLT3 p.Asp835Val (p.D835V) ( ENST00000241453.12 ) FLT3 p.Asp835Val (p.D835V) ( ENST00000241453.12 ) |
Sensitivity | true | CIViC Evidence | detail |