TNF
Information
- Drug Name
- TNF
- Description
- Entry(CIViC)
CIViC
[No Data.]
Annotation
| Description | Associated Genes | Associated Variants | Sensitivity | Supported | Source | Links |
|---|---|---|---|---|---|---|
| MEK1/2 plays an important role in TNFalpha-resista... | MAP2K7 | MAP2K7 UNDEREXPRESSION | Sensitivity | true | MMMP | detail |
| MEK1/2 plays an important role in TNFalpha-resista... | PRRT2 | PRRT2 UNDEREXPRESSION | Sensitivity | true | MMMP | detail |
| MEK1/2 plays an important role in TNFalpha-resista... | AKT1 | AKT1 UNDEREXPRESSION | Resitance or Non-Reponse | true | MMMP | detail |
| Results obtained by re-expressing TNFR1 with demet... | TNFRSF1A | TNFRSF1A METHYLATION | Resitance or Non-Reponse | true | MMMP | detail |
| TNF induces NFkB activity, which antagonizes BRAF ... | BRAF | BRAF UNDEREXPRESSION | Resitance or Non-Reponse | true | MMMP | detail |
| HMW-MAA inhibition seems to act through inhibition... | CSPG4 | CSPG4 UNDEREXPRESSION | Sensitivity | true | MMMP | detail |
| NCT ID | Status | Phase | Summary | Start date | Completion date |
|---|---|---|---|---|---|
| NCT05433597 | Not yet recruiting | Phase 2/Phase 3 | A Two-blinded, Multicentre, Phase II/III RCT of Concurrent Chemo-radiotherapy Combined or Not Combined With TNF as the Therapy for LA-NPC | July 1, 2022 | July 1, 2029 |