Annotation Detail
Information
- Associated Genes
- BRAF
- Associated Variants
- BRAF UNDEREXPRESSION
- Source Database
- MMMP
- Description
- TNF induces NFkB activity, which antagonizes BRAF inhibition
- MMMP State
- downregulated by
- MMMP Molecule
- BRAF
- MMMP Molecule Alias
- B-Raf
- MMMP Modifier
- BRAF siRNA
- MMMP Relationship
- resistance to
- MMMP Drug
- TNF
- MMMP Drug Alias
- Tumor necrosis factor
- MMMP Model
- 3
- MMMP Reference
- Gray-Schopfer VC, Cancer Res 2007, 67:122-9
- MMMP DNA/mRNA/Protein
- mRNA
Drugs
| Drug Name | Sensitivity | Supported |
|---|---|---|
| TNF | Resitance or Non-Reponse | true |