Nutlin-3a
Information
- Drug Name
- Nutlin-3a
- Description
- Entry(CIViC)
- 2
CIViC
| Disease | Mutation | EL | ET | ED | CS | VO | TR | Pubmed | Links |
|---|---|---|---|---|---|---|---|---|---|
| cancer | TP53 WILD TYPE TP53 WILD TYPE | D |
Predictive
|
Supports
|
Sensitivity/Response |
N/A
|
4 | 17671205 | Detail |
| cancer | TP53 DELETERIOUS MUTATION TP53 DELETERIOUS MUTATION | D |
Predictive
|
Supports
|
Resistance | Somatic | 4 | 17671205 | Detail |
Annotation
| Description | Associated Genes | Associated Variants | Sensitivity | Supported | Source | Links |
|---|---|---|---|---|---|---|
| MDM2 Inhibitor Nutlin-3a induced senescence in pre... | TP53 | TP53 WILD TYPE TP53 WILD TYPE | Sensitivity | true | CIViC Evidence | detail |
| MDM2 Inhibitor Nutlin-3a induced senescence in pre... | TP53 | TP53 DELETERIOUS MUTATION TP53 DELETERIOUS MUTATION | Resitance or Non-Reponse | true | CIViC Evidence | detail |