tetralogy of Fallot
Information
- Disease name
- tetralogy of Fallot
- Disease ID
- DOID:6419
- Description
Disease area statistics
Chromosome band
| Gene symbol | Chromosome | Start | Stop | The number of variant |
|---|---|---|---|---|
| GATA4 | 8 | 11,704,202 | 11,760,002 | 8 |
Annotation
| Genes | Mutation | Description | Source | Links |
|---|
| NCT ID | Status | Phase | Summary | Start date | Completion date |
|---|---|---|---|---|---|
| NCT03983512 | Active, not recruiting | N/A | PULSTA Transcatheter Pulmonary Valve Pre-Approval Study | October 7, 2019 | August 2026 |
| NCT03130777 | Active, not recruiting | N/A | ALTERRA: SAPIEN 3 THV With the Alterra Adaptive Prestent | August 22, 2017 | June 2032 |
| NCT03441971 | Active, not recruiting | N/A | Evaluation of the GORE PV1 Device in Patients With Pulmonary Valve Dysfunction | June 7, 2018 | March 2025 |
| NCT00266188 | Completed | Follow up of Post-repair Tetralogy of Fallot | January 2005 | June 2008 | |
| NCT00412685 | Completed | Myocardial Contrast Echocardiography in Congenital Heart Disease | August 2006 | December 2008 | |
| NCT00536432 | Completed | Early Re-intervention in Infants and Small Children After Correction of Tetralogy of Fallot | September 2007 | June 2012 | |
| NCT00573066 | Completed | Phase 1 | Understanding Dexmedetomidine In Infants Post-Operative From Cardiac Surgery | May 2004 | October 2006 |
| NCT01915277 | Completed | Phase 1 | A Phase I Study of Dexmedetomidine Bolus and Infusion in Corrective Infant Cardiac Surgery: Safety and Pharmacokinetics | April 2, 2014 | October 17, 2017 |
| NCT00005190 | Completed | Reproduction and Survival After Cardiac Defect Repair | July 1986 | December 1998 | |
| NCT00112320 | Completed | N/A | Comparison of Two Pulmonary Valve Replacement Methods to Treat Tetralogy of Fallot | April 2004 | August 2011 |
| NCT01419756 | Completed | Assessment of Right Ventricular Volume in Tetralogy of Fallott (TOF) Patients | August 2011 | August 2013 | |
| NCT01762124 | Completed | N/A | Study of the Native Outflow Tract Transcatheter Pulmonary Valve (TPV) | October 2012 | July 2020 |
| NCT01824160 | Completed | N/A | Pulmonary Artery Repair With Covered Stents | December 2012 | June 30, 2016 |
| NCT00004361 | Completed | Study of the Relationship Between Calcium Levels and Intact Parathyroid Hormone (iPTH) in Adults With Repaired or Palliated Conotruncal Cardiac Defects | July 1995 | ||
| NCT01941576 | Completed | N/A | Effects of rhBNP in Pediatrics After Corrective Repair of Tetralogy Of Fallot | September 1, 2013 | July 20, 2019 |
| NCT02534792 | Completed | Early Revalvulation After Fallot Repair Improves Clinical Outcome | September 2015 | July 2016 | |
| NCT02586740 | Completed | Retrospective Review of Anesthetic Considerations for Pulmonary Artery Rehabilitation | November 2015 | October 2016 | |
| NCT02643810 | Completed | N/A | Exercise Training in Adults With Corrected Tetralogy of Fallot | June 2015 | March 5, 2017 |
| NCT02967315 | Completed | N/A | Effects of Changes in Fluid Status on Right Ventricular Volumes and Function | June 6, 2014 | March 18, 2021 |
| NCT02968264 | Completed | Tetralogy of Fallot for Life | June 8, 2015 | July 1, 2022 | |
| NCT03835494 | Completed | N/A | Analysis of RV-Dysfunction in Fallot Patients | November 1, 2018 | February 28, 2019 |
| NCT04452188 | Completed | N/A | Targeting Normoxia in Neonates With Cyanotic Congenital Heart Disease in the Intra-operative and Immediate Post-operative Period | January 18, 2021 | April 20, 2023 |
| NCT05579964 | Completed | Phase 2/Phase 3 | The Role of Dexmedetomidine as Myocardial Protector in Pediatric Cardiac Surgery Total Correction of Tetralogy of Fallot | October 10, 2022 | June 10, 2023 |
| NCT05976204 | Completed | Prognostic Value of NLR, TLR, and ALC in Predicting ToF Primary Repair Outcome | January 1, 2020 | June 30, 2023 | |
| NCT06097377 | Completed | Lymphatic Magnetic Resonance Imaging Abnormalities in Children With Tetralogy of Fallot: A Case-Control Study | November 1, 2021 | September 1, 2023 | |
| NCT04288596 | Not yet recruiting | Canadian Adult Congenital Heart Disease Intervention Registry | April 1, 2020 | April 1, 2030 | |
| NCT05916976 | Not yet recruiting | N/A | Repaired Tetralogy of Fallot: Risc Score From MRI & Clinical Data to Predict the Need for Change of Treatment | October 15, 2023 | April 30, 2026 |
| NCT05485545 | Not yet recruiting | N/A | Asynchrony in Operated Tetralogy of Fallot | September 1, 2022 | September 1, 2024 |
| NCT06081855 | Not yet recruiting | Predictors of Aortic Root Dilatation in Tetralogy of Fallot Patients | January 1, 2024 | May 1, 2025 | |
| NCT06282926 | Not yet recruiting | Role of 3D Echocardiography Knowledge-based Reconstruction in ACHD | March 2024 | September 2025 | |
| NCT05186415 | Recruiting | Phase 1/Phase 2 | Contrast Enhanced Three Dimensional Echocardiographic Quantification of Right Ventricular Volumes in Repaired Congenital Heart Disease | August 23, 2022 | July 2024 |
| NCT05288894 | Recruiting | Repaired Tetralogy of Fallot Italian Registry | March 1, 2021 | March 2027 | |
| NCT05378386 | Recruiting | ALTERRA Post-Approval Study | May 12, 2022 | December 2034 | |
| NCT03470064 | Recruiting | Early Right Ventricular Function After Repair Of Tetralogy Of Fallot , An Evidence Based Study. | April 1, 2018 | October 1, 2022 | |
| NCT04581668 | Recruiting | N/A | Impact of NAVA Ventilation on Brain Oxygenation and Perfusion in Children With Congenital Heart Disease | October 5, 2020 | December 1, 2023 |
| NCT04713657 | Recruiting | Phase 1 | Beta-blocker Administration for Cardiomyocyte Division | December 16, 2022 | February 1, 2026 |
| NCT05122962 | Recruiting | Pathophysiologic Mechanism for Arrhythmias and Impaired Aerobic Capacity in Tetralogy of Fallot and Other Congenital Heart Diseases | November 1, 2021 | October 2026 | |
| NCT05236153 | Recruiting | N/A | Electroanatomic Interactions Between Transcatheter Pulmonary Valve Prostheses and Anatomic Isthmuses in Repaired Tetralogy of Fallot | November 4, 2022 | January 1, 2024 |
| NCT05809310 | Recruiting | N/A | Effects Branch PA Stenting d-TGA, ToF and TA | April 18, 2023 | September 30, 2025 |
| NCT03837574 | Recruiting | French National Registry of Patients With Tetralogy of Fallot and Implantable Cardioverter Defibrillator | December 1, 2010 | December 31, 2030 | |
| NCT00243776 | Recruiting | Molecular and Cellular Characterization of Cardiac Tissue in Postnatal Development | April 2005 | December 31, 2025 | |
| NCT04084132 | Recruiting | N/A | Early Versus Later Re-valving in Tetralogy of Fallot With Free Pulmonary Regurgitation | April 1, 2019 | December 31, 2031 |
| NCT04106479 | Recruiting | NIRS in Congenital Heart Defects - Correlation With Echocardiography | October 11, 2019 | December 1, 2024 | |
| NCT04208893 | Suspended | N/A | Exercise Training Strategies for Children With Repaired Tetralogy of Fallot | August 20, 2019 | August 31, 2022 |
| NCT03634072 | Terminated | N/A | Pediatric REPlAcement of the PulmonaRy ValvE in Tetralogy of Fallot - | July 6, 2018 | January 16, 2021 |
| NCT01971593 | Terminated | Phase 4 | The Effects of Eplerenone on Markers of Myocardial Fibrosis in Adult Congenital Heart Disease | August 2013 | June 2016 |
| NCT00564993 | Terminated | Phase 3 | Cardiac Function Under Stress for Early Detection of the Right Ventricular Insufficiency After Repair of Tetralogy of Fallot | November 2007 | May 2012 |
| NCT00860327 | Terminated | Examining Developmental Changes in Heart Contractions of Children With Congenital Heart Defects | December 2007 | June 2016 | |
| NCT04359940 | Unknown status | Effect of Contouring Techniques on CMR Assessment of the Right Ventricle in Repaired Tetraology of Fallot | January 1, 2013 | April 14, 2020 | |
| NCT03049995 | Unknown status | Stress Echo 2020 - The International Stress Echo Study | November 2016 | December 2021 | |
| NCT03234582 | Unknown status | Comparison of RVOT Gradient Under Anaesthesia With Post-operative Gradient in Patients Undergoing TOF Repair | July 1, 2017 | August 31, 2018 | |
| NCT03275844 | Unknown status | Physical Capacity and Activity in Children With Congenital Heart Disease | November 1, 2017 | September 1, 2018 | |
| NCT03568357 | Unknown status | Reoxygenation for Cyanotic Pediatric CHD | January 1, 2012 | December 31, 2018 | |
| NCT00155428 | Unknown status | N/A | Biomodel in Tetralogy of Fallot | May 2005 | December 2008 |
| NCT02980614 | Unknown status | N/A | 4D Velocity Mapping of the Heart in rTOF Patients | March 27, 2017 | December 2019 |
| NCT02010905 | Unknown status | Phase 2 | Right Ventricular Dysfunction in Tetralogy of Fallot: Inhibition of the Renin-angiotensin-aldosterone System | December 2013 | January 2018 |
| NCT02161471 | Unknown status | Haemodynamics and Function of the Atria in Congenital Heart Disease by Cardiovascular Magnetic Resonance | October 2009 | December 2020 | |
| NCT02590679 | Unknown status | Phase 2/Phase 3 | Multi-center Trial of Percutaneous Pulmonary Valve Implantation With Venus-p | May 2013 | February 2017 |
- Disase is a (Disease Ontology)
- DOID:1682
- Cross Reference ID (Disease Ontology)
- GARD:2245
- Cross Reference ID (Disease Ontology)
- ICD10CM:Q21.3
- Cross Reference ID (Disease Ontology)
- ICD9CM:745.2
- Cross Reference ID (Disease Ontology)
- MESH:D013771
- Cross Reference ID (Disease Ontology)
- MIM:187500
- Cross Reference ID (Disease Ontology)
- NCI:C84505
- Cross Reference ID (Disease Ontology)
- SNOMEDCT_US_2023_03_01:156913009
- Cross Reference ID (Disease Ontology)
- UMLS_CUI:C0039685
- Exact Synonym (Disease Ontology)
- Ventricular septal defect with pulmonary stenosis or atresia, dextraposition of aorta, and hypertrophy of right ventricle
- HPO Human Phenotype ID (Human Phenotype Ontology)
- HP:0001636
- OrphaNumber from OrphaNet (Orphanet)
- 3303
- ICD10 preferred id (Insert disease from ICD10)
- D0013655
- ICD10 class code (Insert disease from ICD10)
- Q21.3
- MeSH unique ID (MeSH (Medical Subject Headings))
- D013771