Annotation Detail
Information
- Associated Genes
- MGMT
- Associated Variants
- MGMT EXPRESSION
- Source Database
- MMMP
- Description
- The 93 patients were treated with DTIC or TMZ. Leucopenia and thrombocytopenia were more prevalent amongst patients with low pre-treatment MGMT expression in PBMC
- MMMP State
- expressed
- MMMP Molecule
- MGMT
- MMMP Molecule Alias
- O-6-methylguanine-DNA methyltransferase
- MMMP Relationship
- toxicity decreased for
- MMMP Drug
- Dacarbazine
- MMMP Drug Alias
- DTIC
- MMMP Model
- 5
- MMMP Reference
- Sabharwal A, Melanoma Res 2009, Epub ahead of print
Drugs
| Drug Name | Sensitivity | Supported |
|---|---|---|
| Dacarbazine | toxicity decrease | true |