Annotation Detail
Information
- Associated Genes
- MGMT
- Associated Variants
- MGMT EXPRESSION
- Source Database
- MMMP
- Description
- Original: underexpression associated with increased toxicity
- MMMP State
- expressed
- MMMP Molecule
- MGMT
- MMMP Molecule Alias
- O-6-methylguanine-DNA methyltransferase
- MMMP Relationship
- toxicity decreased for
- MMMP Drug
- Temozolomide
- MMMP Drug Alias
- TMZ
- MMMP Model
- 5
- MMMP Reference
- Middleton MR, Int J Cancer 2000, 88:469-73
Drugs
| Drug Name | Sensitivity | Supported |
|---|---|---|
| Temozolomide | toxicity decrease | true |