Annotation Detail

Information
Associated Genes
MYC
Associated Variants
MYC UNDEREXPRESSION
Source Database
MMMP
Description
In vivo experiments revealed that liposomal formulations of c-Myc antisense and DXR, both delivered via liposomes targeted with a monoclonal antibody against the disialoganglioside GD(2), led to the most pronounced delay in tumor growth when administered in a sequential manner
MMMP State
downregulated by
MMMP Molecule
MYC
MMMP Molecule Alias
c-Myc
MMMP Modifier
MYC antisense oligo
MMMP Relationship
sensitivity to
MMMP Drug
Doxorubicin
MMMP Drug Alias
Adriamycin (R)
MMMP Model
4
MMMP Reference
Pastorino F, J Control Release 2008, 126:85-94
MMMP DNA/mRNA/Protein
mRNA
Drugs
Drug NameSensitivitySupported
DoxorubicinSensitivitytrue