Annotation Detail
Information
- Associated Genes
- MGMT
- Associated Variants
- MGMT EXPRESSION
- Source Database
- MMMP
- Description
- MGMT showed a significant correlation with temozolomide sensitivity (MGMT activity, P < 0.0001; MGMT expression, P ≤ 0.0001).
- MMMP State
- expressed
- MMMP Molecule
- MGMT
- MMMP Molecule Alias
- O-6-methylguanine-DNA methyltransferase
- MMMP Relationship
- resistance to
- MMMP Drug
- Temozolomide
- MMMP Drug Alias
- TMZ
- MMMP Model
- 3
- MMMP Reference
- Augustine CK, Clin Cancer Res 2009, 15:502-10
Drugs
| Drug Name | Sensitivity | Supported |
|---|---|---|
| Temozolomide | Resitance or Non-Reponse | true |