Annotation Detail

Information
Associated Genes
MGMT
Associated Variants
MGMT UNDEREXPRESSION
Source Database
MMMP
Description
Isolated limb infusion model (locoregional therapy)
MMMP Drug Alias
TMZ
MMMP Model
4
MMMP State
inhibited by
MMMP Molecule
MGMT
MMMP Molecule Alias
O-6-methylguanine-DNA methyltransferase
MMMP Modifier
O-6-benzylguanidine
MMMP Relationship
sensitivity to
MMMP Drug
Temozolomide
MMMP Reference
Ueno T, Mol Cancer Ther 2006, 5:732-8
MMMP DNA/mRNA/Protein
protein
Drugs
Drug NameSensitivitySupported
TemozolomideSensitivitytrue