Annotation Detail
Information
- Associated Genes
- MGMT
- Associated Variants
- MGMT UNDEREXPRESSION
- Source Database
- MMMP
- Description
- IBgBZ is designed as a conjugate of O(6)-(4-iododbenzyl)guanine (IBg) as the MGMT inactivator and a N,N-diethylaminoethylenebenzamido (BZ) moiety as the carrier to the malignant melanocytes
- MMMP State
- inhibited by
- MMMP Molecule
- MGMT
- MMMP Molecule Alias
- O-6-methylguanine-DNA methyltransferase
- MMMP Modifier
- IBgBZ
- MMMP Relationship
- sensitivity to
- MMMP Drug
- Cystemustine
- MMMP Model
- 4
- MMMP Reference
- Rapp M, J Pharmacol Exp Ther 2008, 326:171-7
- MMMP DNA/mRNA/Protein
- protein
Drugs
| Drug Name | Sensitivity | Supported |
|---|---|---|
| Cystemustine | Sensitivity | true |