Annotation Detail
Information
- Associated Genes
- MGMT
- Associated Variants
- MGMT UNDEREXPRESSION
- Source Database
- MMMP
- Description
- Coincubation of melanoma cells with O6-benzylguanine significantly increased the cytotoxicity of fotemustine
- MMMP State
- inhibited by
- MMMP Molecule
- MGMT
- MMMP Molecule Alias
- O-6-methylguanine-DNA methyltransferase
- MMMP Modifier
- O-6-benzylguanidine
- MMMP Relationship
- sensitivity to
- MMMP Drug
- Fotemustine
- MMMP Model
- 3
- MMMP Reference
- Passagne I, J Pharmacol Exp Ther 2003, 307:816-23
- MMMP DNA/mRNA/Protein
- protein
Drugs
| Drug Name | Sensitivity | Supported |
|---|---|---|
| Fotemustine | Sensitivity | true |