Annotation Detail
Information
- Associated Genes
- MGMT
- Associated Variants
- MGMT EXPRESSION
- Source Database
- MMMP
- Description
- Uveal melanoma. These results do not support MGMT methylation status or protein expression as predictive markers for treatment outcome to intra-arterial chemotherapy with alkylating agents
- MMMP State
- expressed
- MMMP Molecule
- MGMT
- MMMP Molecule Alias
- O-6-methylguanine-DNA methyltransferase
- MMMP Relationship
- no relationship with
- MMMP Drug
- Fotemustine
- MMMP Model
- 5
- MMMP Reference
- Voelter V et al, Int J Cancer 2008, 123:1215-8
- MMMP DNA/mRNA/Protein
- protein
Drugs
| Drug Name | Sensitivity | Supported |
|---|---|---|
| Fotemustine | Resitance or Non-Reponse | true |