Annotation Detail
Information
- Associated Genes
- MGMT
- Associated Variants
- MGMT UNDEREXPRESSION
- Source Database
- MMMP
- Description
- 4BTG was less toxic (but equally effective) than O6-benzylguanine
- MMMP State
- inhibited by
- MMMP Molecule
- MGMT
- MMMP Molecule Alias
- O-6-methylguanine-DNA methyltransferase
- MMMP Modifier
- 4BTG
- MMMP Modifier Alias
- O(6)-(4-bromothenyl)guanine
- MMMP Relationship
- sensitivity to
- MMMP Drug
- Temozolomide
- MMMP Drug Alias
- TMZ
- MMMP Model
- 4
- MMMP Reference
- Middleton MR, Int J Cancer 2000, 85:248-52
- MMMP DNA/mRNA/Protein
- protein
Drugs
Drug Name | Sensitivity | Supported |
---|---|---|
Temozolomide | Sensitivity | true |