Annotation Detail

Information
Associated Genes
MGMT
Associated Variants
MGMT UNDEREXPRESSION
Source Database
MMMP
Description
MGMT causes resistance to TMZ
MMMP State
inhibited by
MMMP Molecule
MGMT
MMMP Molecule Alias
O-6-methylguanine-DNA methyltransferase
MMMP Modifier
O-6-benzylguanine
MMMP Relationship
sensitivity to
MMMP Drug
Temozolomide
MMMP Drug Alias
TMZ
MMMP Model
3
MMMP Reference
Fontijn D, Mol Cancer Ther 2007, 6:2807-15
MMMP DNA/mRNA/Protein
protein
Drugs
Drug NameSensitivitySupported
TemozolomideSensitivitytrue