Annotation Detail

Information
Associated Genes
MGMT
Associated Variants
MGMT EXPRESSION
Source Database
MMMP
Description
There was an inverse relationship between MGMT expression and clinical response to DTIC-based chemotherapy
MMMP State
expressed
MMMP Molecule
MGMT
MMMP Molecule Alias
O-6-methylguanine-DNA methyltransferase
MMMP Relationship
resistance to
MMMP Drug
Dacarbazine based chemotherapy
MMMP Model
5
MMMP Reference
Ma S, Br J Cancer 2003, 89:1517-23
MMMP DNA/mRNA/Protein
protein
Drugs
Drug NameSensitivitySupported
Dacarbazine based chemotherapyResitance or Non-Reponsetrue