Annotation Detail

Information
Associated Genes
IL6
Associated Variants
IL6 MUTATION
IL6 MUTATION
Associated Disease
Non-small cell lung carcinoma
Source Database
DisGeNET
Description
NOX4/Akt and IL-6/STAT3 signalings can reciprocally and positively regulate each other, leading to enhanced NSCLC cell proliferation and survival.
Pubmed
25504436
Section of the abstract supporting the evidence
ALL_TEXT_3/3
Number of the section of the abstract supporting the evidence
3
Number of the sentence supporting the evidence
11
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.00570027931368637
Drugs