Annotation Detail

Information
Associated Genes
VEGFA
Associated Variants
VEGFA MUTATION
VEGFA MUTATION
Associated Disease
Non-small cell lung carcinoma
Source Database
DisGeNET
Description
These results suggest that low dose erlotinib-cisplatin combination exhibits its anti-tumor activity by targeting angiogenesis through the modulation of the c-MYC/HIF-1α/VEGF pathway in NSCLC with EGFR exon 19 deletions.
Pubmed
25748238
Section of the abstract supporting the evidence
ALL_TEXT_3/3
Number of the section of the abstract supporting the evidence
3
Number of the sentence supporting the evidence
9
Original source reporting the Gene Disease association
BeFree,CTD_human,GAD
DisGENET score for the Gene Disease association
0.148696893570391
Drugs