Annotation Detail

Information
Associated Genes
STAT3
Associated Variants
STAT3 MUTATION
STAT3 MUTATION
Associated Disease
Non-small cell lung carcinoma
Source Database
DisGeNET
Description
This study also suggests that STAT3 inhibitors may aid in the treatment NSCLC patients who exhibit EGFR‑TKI resistance due to an acquired T790M mutation.
Pubmed
25695284
Section of the abstract supporting the evidence
ALL_TEXT_3/3
Number of the section of the abstract supporting the evidence
3
Number of the sentence supporting the evidence
11
Original source reporting the Gene Disease association
BeFree,CTD_human
DisGENET score for the Gene Disease association
0.130857674883212
Drugs