Annotation Detail

Information
Associated Genes
CASP8
Associated Variants
CASP8 MUTATION
CASP8 MUTATION
Associated Disease
Non-small cell lung carcinoma
Source Database
DisGeNET
Description
Gefitinib induces cytoplasmic translocation of the CDK inhibitor p27 and its binding to a cleaved intermediate of caspase 8 in non-small cell lung cancer cells.
Pubmed
25228008
Section of the abstract supporting the evidence
TITLE
Number of the section of the abstract supporting the evidence
0
Number of the sentence supporting the evidence
0
Original source reporting the Gene Disease association
BeFree,CTD_human
DisGENET score for the Gene Disease association
0.122714418720803
Drugs