Annotation Detail

Information
Associated Genes
KMT2A
Associated Variants
KMT2A MUTATION
KMT2A MUTATION
Associated Disease
bronchopulmonary dysplasia
Source Database
DisGeNET
Description
These data support the hypothesis that hyperoxic impairment of Trx1 has a negative impact on HSP90-oxidative responses critical to cell survival, with potential implications for pathways implicated in lung development and the pathogenesis of BPD.
Pubmed
25106706
Section of the abstract supporting the evidence
ALL_TEXT_3/3
Number of the section of the abstract supporting the evidence
3
Number of the sentence supporting the evidence
16
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.000271441872080303
Drugs