Annotation Detail
Information
- Associated Genes
- EIF3H
- Associated Variants
-
rs10795668
POU2AF3 c.102+363C>A ( ENST00000526216.1, ENST00000398035.6, ENST00000638573.1, ENST00000614153.4, ENST00000610738.6 )
rs4444235
rs4779584
CDH1 c.164-14627G>A ( ENST00000261769.10, ENST00000422392.6 )
SMAD7 c.743-5183A>G ( ENST00000262158.8, ENST00000589634.1, ENST00000591805.5 )
RHPN2 c.185+2855G>A ( ENST00000254260.8 )
rs961253
rs16892766
rs6983267 ( ENST00000645438.1 )
rs10795668
POU2AF3 c.102+363C>A ( ENST00000398035.6, ENST00000526216.1, ENST00000610738.6, ENST00000614153.4, ENST00000638573.1 )
rs4444235
rs4779584
CDH1 c.164-14627G>A ( ENST00000261769.10, ENST00000422392.6 )
SMAD7 c.743-5183A>G ( ENST00000262158.8, ENST00000589634.1, ENST00000591805.5 )
RHPN2 c.185+2855G>A ( ENST00000254260.8 )
rs961253
rs16892766
rs6983267 ( ENST00000645438.1 ) - Associated Disease
- colorectal carcinoma
- Source Database
- DisGeNET
- Description
- We used meta-analysis of an efficient empirical-Bayes estimator to detect potential multiplicative interactions between each of the SNPs [rs16892766 at 8q23.3 (EIF3H/UTP23), rs6983267 at 8q24 (MYC), rs10795668 at 10p14 (FLJ3802842), rs3802842 at 11q23 (LOC120376), rs4444235 at 14q22.2 (BMP4), rs4779584 at 15q13 (GREM1), rs9929218 at 16q22.1 (CDH1), rs4939827 at 18q21 (SMAD7), rs10411210 at 19q13.1 (RHPN2), and rs961253 at 20p12.3 (BMP2)] and select major CRC risk factors (sex, body mass index, height, smoking status, aspirin/nonsteroidal anti-inflammatory drug use, alcohol use, and dietary intake of calcium, folate, red meat, processed meat, vegetables, fruit, and fiber).
- Pubmed
- 22367214
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.00081432561624091
- Year of publication
- 2012
Drugs