Annotation Detail

Information
Associated Genes
TP53
Associated Variants
TP53 MUTATION
TP53 MUTATION
Associated Disease
Barrett esophagus
Source Database
DisGeNET
Description
Immunostaining for p53 is the only candidate biomarker deemed ready for prime time. This has been recommended for use clinically as an adjunct to histological diagnosis of dysplastic Barrett's esophagus in the 2014 British Society of Gastroenterology guidelines on the diagnosis and management of Barrett's esophagus.
Pubmed
24844657
Section of the abstract supporting the evidence
RECENT FINDINGS
Number of the section of the abstract supporting the evidence
2
Number of the sentence supporting the evidence
7
Original source reporting the Gene Disease association
BeFree,GAD,LHGDN
DisGENET score for the Gene Disease association
0.00908706543215305
Drugs