Annotation Detail
Information
- Associated Genes
- IL4
- Associated Variants
-
LUC7L c.807-146T>G
(
ENST00000397783.5,
ENST00000337351.8,
ENST00000629543.2,
ENST00000293872.13,
ENST00000397780.5 )
IL4R p.Ser503Pro (p.S503P) ( ENST00000543915.6, ENST00000395762.7, ENST00000170630.6 )
ENSG00000266202 c.438+1937C>T
IL1A p.Ala114Ser (p.A114S) ( ENST00000263339.4 )
rs2243250
NC_000006.12:g.31575186G>A
CD40LG p.Leu50= (p.L50=) ( ENST00000370628.2, ENST00000370629.7, ENST00000695724.1, ENST00000695725.1 )
LUC7L c.807-146T>G ( ENST00000293872.13, ENST00000337351.8, ENST00000397780.5, ENST00000397783.5, ENST00000629543.2 )
IL4R p.Ser503Pro (p.S503P) ( ENST00000170630.6, ENST00000395762.7, ENST00000543915.6 )
ENSG00000266202 c.438+1937C>T
IL1A p.Ala114Ser (p.A114S) ( ENST00000263339.4 )
rs2243250
NC_000006.12:g.31575186G>A
CD40LG p.Leu50= (p.L50=) ( ENST00000370628.2, ENST00000370629.7, ENST00000695724.1, ENST00000695725.1 ) - Associated Disease
- malaria
- Source Database
- DisGeNET
- Description
- A GTGTGTC haplotype consisting of IL-1A (rs17561), IL-4 (rs2243250), TNF (rs1800750), IL-4R (rs1805015), NOS (rs8078340), CD40LG (rs1126535), and LUC7L (rs1211375) was significantly associated with the prevalence of malaria (POR: 1.822, 95% CI: 0.998-3.324).
- Pubmed
- 26448013
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.00997733591851466
- Year of publication
- 2016
Drugs