Annotation Detail

Information
Associated Genes
TLR3
Associated Variants
TLR3 MUTATION
TLR3 MUTATION
Associated Disease
Astrocytoma
Source Database
DisGeNET
Description
In the present study, pretreatment of U373MG human astrocytoma cells with an iron chelator desferrioxamine (DFX) inhibited the expression of CXCL10 induced by a Toll-like receptor 3 (TLR3) agonist polyinosinic-polycytidylic acid (poly IC).
Pubmed
25591911
Section of the abstract supporting the evidence
ALL_TEXT_1/3
Number of the section of the abstract supporting the evidence
1
Number of the sentence supporting the evidence
3
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.000271441872080303
Drugs