Annotation Detail
Information
- Associated Genes
- CCR5
- Associated Variants
-
CCR5 MUTATION
CCR5 MUTATION - Associated Disease
- rheumatoid arthritis
- Source Database
- DisGeNET
- Description
- In addition to the strong association between alleles of the HLA-DRB1*04 shared epitope and both subclinical and clinically evident CV disease, genes implicated in inflammation and metabolism, such as TNFA, MTHFR, and CCR5, seem to be associated with a higher risk of CV disease in patients with RA.
- Pubmed
- 25163740
- Section of the abstract supporting the evidence
- ALL_TEXT_3/3
- Number of the section of the abstract supporting the evidence
- 3
- Number of the sentence supporting the evidence
- 5
- Original source reporting the Gene Disease association
- BeFree,GAD,LHGDN
- DisGENET score for the Gene Disease association
- 0.0319853287319991
Drugs