Annotation Detail
Information
- Associated Genes
- ESR1
- Associated Variants
-
ESR1 MUTATION
ESR1 MUTATION - Associated Disease
- aortic valve insufficiency
- Source Database
- DisGeNET
- Description
- Aromatase inhibitors (AIs) are the standard endocrine therapy for postmenopausal breast cancer; however, currently used biomarkers, such as, estrogen receptor-alpha/progesterone receptor (ERα/PR), predict only slightly more than half of the potential responders to AI treatment.
- Pubmed
- 24413080
- Section of the abstract supporting the evidence
- ALL_TEXT_1/3
- Number of the section of the abstract supporting the evidence
- 1
- Number of the sentence supporting the evidence
- 1
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.000542883744160607
Drugs