Annotation Detail
Information
- Associated Genes
- SOCS1
- Associated Variants
-
SOCS1 MUTATION
SOCS1 MUTATION - Associated Disease
- Cirrhosis
- Source Database
- DisGeNET
- Description
- We found high frequencies of SOCS1 gene hypermethylation in both tumour (56.03%) and adjacent nontumour tissues (54.31%), but tumour tissues exhibited increased methylation intensity (24.01% vs 13.11%, P < 0.0001), particularly in patients with larger tumour size or cirrhosis background (P < 0.0001).
- Pubmed
- 23941364
- Section of the abstract supporting the evidence
- ALL_TEXT_2/3
- Number of the section of the abstract supporting the evidence
- 2
- Number of the sentence supporting the evidence
- 7
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.00108576748832121
Drugs