Annotation Detail

Information
Associated Genes
TNF
Associated Variants
TNF MUTATION
TNF MUTATION
Associated Disease
severe acute respiratory syndrome
Source Database
DisGeNET
Description
Through our genomics-based approach, we found topological differences in the kinetics and magnitude of the host response to MERS-CoV SA 1 and MERS-CoV Eng 1, with differential expression of innate immune and pro-inflammatory responsive genes as a result of IFN, TNF and IL-1α signaling.
Pubmed
25534508
Section of the abstract supporting the evidence
CONCLUSIONS
Number of the section of the abstract supporting the evidence
3
Number of the sentence supporting the evidence
8
Original source reporting the Gene Disease association
BeFree,GAD
DisGENET score for the Gene Disease association
0.0100110116585687
Drugs