Annotation Detail
Information
- Associated Genes
- ABCG2
- Associated Variants
-
ABCG2 MUTATION
ABCG2 MUTATION - Associated Disease
- hyperuricemia
- Source Database
- DisGeNET
- Description
- Because ABCG2 dysfunctional diplotypes were commonly observed in both Caucasians (16.5%) and African-Americans (16.0%), the genotyping of the two ABCG2 dysfunctional variants is useful for evaluating individual differences in the ABCG2 dysfunction which affect the pharmacokinetics of substrate drugs and hyperuricemia risk in all three ethnic groups.
- Pubmed
- 24869748
- Section of the abstract supporting the evidence
- ALL_TEXT_3/3
- Number of the section of the abstract supporting the evidence
- 3
- Number of the sentence supporting the evidence
- 7
- Original source reporting the Gene Disease association
- BeFree,GAD
- DisGENET score for the Gene Disease association
- 0.013811197867693
Drugs