Annotation Detail
Information
- Associated Genes
- F2R
- Associated Variants
-
F2R MUTATION
F2R MUTATION
HTR2A p.Ser34= (p.S34=) ( ENST00000542664.4, ENST00000543956.5 )
HTR1A c.-1019G>C
HTR2A p.Ser34= (p.S34=) ( ENST00000542664.4, ENST00000543956.5 )
HTR1A c.-1019G>C - Associated Disease
- schizophrenia
- Source Database
- DisGeNET
- Description
- While further research into the molecular mechanisms underlying this interaction is needed, our results underscore the role of 5-HTR in PPI modulation and further implicate the 5-HTR1A G-1019C and the 5-HTR2A T102C polymorphisms in the pathophysiology of schizophrenia.
- Pubmed
- 19352591
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.00081432561624091
- Year of publication
- 2009
Drugs