Annotation Detail
Information
- Associated Genes
- CXCL8
- Associated Variants
-
NC_000004.12:g.73740307A>T
CD14 c.-221-39T>C ( ENST00000498971.7, ENST00000512545.2, ENST00000519715.2 )
NC_000004.12:g.73740307A>T
CD14 c.-221-39T>C ( ENST00000498971.7, ENST00000512545.2, ENST00000519715.2 ) - Associated Disease
- Severe Sepsis
- Source Database
- DisGeNET
- Description
- Genotypes GG of rs2569190 (the CD14 gene) and AT of rs4073 (the IL8 gene) were associated with a significantly increased risk of developing severe sepsis (p = 0.05 and p = 0.01).
- Pubmed
- 25000179
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.000542883744160607
- Year of publication
- 2014
Drugs