Annotation Detail
Information
- Associated Genes
- IL1B
- Associated Variants
-
IL1B MUTATION
IL1B MUTATION - Associated Disease
- Intervertebral Disc Degeneration
- Source Database
- DisGeNET
- Description
- We investigated whether expression of xylosyltransferase-1 (XT-1), a key enzyme in glycosaminoglycan biosynthesis, is responsive to disk degeneration and to inhibition by the inflammatory cytokines tumor necrosis factor α and IL-1β in nucleus pulposus (NP) cells.
- Pubmed
- 25476526
- Section of the abstract supporting the evidence
- ALL_TEXT_1/3
- Number of the section of the abstract supporting the evidence
- 1
- Number of the sentence supporting the evidence
- 1
- Original source reporting the Gene Disease association
- BeFree,GAD
- DisGENET score for the Gene Disease association
- 0.00663415706176619
Drugs