Annotation Detail
Information
- Associated Genes
- COMT
- Associated Variants
-
COMT MUTATION
COMT MUTATION - Associated Disease
- Uterine Fibroids
- Source Database
- DisGeNET
- Description
- The genetic polymorphisms of IVS1+2329C>T and Val158Met loci in COMT, Ile462Val and Gly45Asp loci in CYP1A1 and Ala119Ser loci in CYP1B1 were risk factors for uterine leiomyoma development, and Leu432Val locus in CYB1B1 may be a protective factor.
- Pubmed
- 24320736
- Section of the abstract supporting the evidence
- CONCLUSION
- Number of the section of the abstract supporting the evidence
- 4
- Number of the sentence supporting the evidence
- 7
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.00244297684872273
Drugs