Annotation Detail
Information
- Associated Genes
- MYC
- Associated Variants
-
rs3024505
IL19 c.-149+1984T>G ( ENST00000659642.2, ENST00000659997.3, ENST00000656872.2, ENST00000659065.2, ENST00000664374.2 )
rs6983267 ( ENST00000645438.1 )
rs3024505
IL19 c.-149+1984T>G ( ENST00000659065.2, ENST00000659642.2, ENST00000664374.2, ENST00000656872.2, ENST00000659997.3 )
rs6983267 ( ENST00000645438.1 ) - Associated Disease
- colorectal cancer
- Source Database
- DisGeNET
- Description
- We found indications that aspirin interacted with rs6983267 close to MYC (encoding a transcription factor involved in cell cycle progression, apoptosis and cellular transformation) and NSAIDs interacted with rs3024505 and rs1800872 in or close to IL10 (encoding IL-10) in preventing CRC.
- Pubmed
- 24889212
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.011324613757252
- Year of publication
- 2014
Drugs