Annotation Detail
Information
- Associated Genes
- TNF
- Associated Variants
-
TNF c.-488G>A
TNF c.-488G>A - Associated Disease
- Nasal Polyps
- Source Database
- DisGeNET
- Description
- The frequency of the A allele in a SNP located in tumor necrosis factor (TNF)-alpha (rs1800629) is significantly different in patients with nasal polyposis versus controls without nasal polyposis, 18.6% and 11.5%, respectively with an individuals' odds of susceptibility to nasal polyps increasing almost two-fold (odds ratio, 1.86; confidence interval, 1.4-3.09) given at least one copy of the A allele at this SNP.
- Pubmed
- 19405090
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.016178229846295
- Year of publication
- 2009
Drugs