Annotation Detail
Information
- Associated Genes
- STAT3
- Associated Variants
-
STAT3 MUTATION
STAT3 MUTATION - Associated Disease
- ovarian carcinoma
- Source Database
- DisGeNET
- Description
- Altogether, our results demonstrate that targeting JAK1/STAT3, using shRNA knockdown or a small-molecule inhibitor, effectively suppressed ovarian tumor progression and, therefore, could be a potential novel therapeutic approach for treating advanced ovarian cancer.
- Pubmed
- 25319391
- Section of the abstract supporting the evidence
- ALL_TEXT_3/3
- Number of the section of the abstract supporting the evidence
- 3
- Number of the sentence supporting the evidence
- 8
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.0081432561624091
Drugs