Annotation Detail

Information
Associated Genes
IL9
Associated Variants
TGFB1 c.-1347T>C ( ENST00000539627.5, ENST00000604123.5 )
CCR2 p.Val64Ile (p.V64I) ( ENST00000400888.2, ENST00000445132.3 )
IL9 p.Thr117Met (p.T117M) ( ENST00000274520.2 )
NC_000006.12:g.31575186G>A
TNF c.-488G>A
NOS3 c.-51-665C>T ( ENST00000297494.8, ENST00000461406.5 )
TGFB1 c.-1347T>C ( ENST00000539627.5, ENST00000604123.5 )
CCR2 p.Val64Ile (p.V64I) ( ENST00000400888.2, ENST00000445132.3 )
IL9 p.Thr117Met (p.T117M) ( ENST00000274520.2 )
NC_000006.12:g.31575186G>A
TNF c.-488G>A
NOS3 c.-51-665C>T ( ENST00000297494.8, ENST00000461406.5 )
Associated Disease
Common Migraine
Source Database
DisGeNET
Description
Among active migraine with aura, the odds ratios (95% confidence intervals) were 1.35 (1.0 to 1.81) for TNF rs1800750, 1.13 (1.02 to 1.26) for TNF rs1800629, and 1.22 (1.07 to 1.40) for CCR2 rs1799864; among active migraine without aura, 0.9 (0.84 to 0.97) for TGFB1 rs1800469, 1.13 (1.01 to 1.27) for NOS3 rs3918226, and 1.12 (1.02 to 1.24) for IL9 rs2069885.
Pubmed
19559392
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.000271441872080303
Year of publication
2009
Drugs