Annotation Detail
Information
- Associated Genes
- CXCL8
- Associated Variants
-
rs2057768
IL19 c.-149+2474T>C ( ENST00000656872.2, ENST00000659642.2, ENST00000659997.3, ENST00000664374.2, ENST00000659065.2 )
NC_000002.12:g.112837290A>G
NC_000004.12:g.73740307A>T
TNF c.-488G>A
rs2057768
IL19 c.-149+2474T>C ( ENST00000659065.2, ENST00000659642.2, ENST00000664374.2, ENST00000656872.2, ENST00000659997.3 )
NC_000002.12:g.112837290A>G
NC_000004.12:g.73740307A>T
TNF c.-488G>A - Associated Disease
- gastric adenocarcinoma
- Source Database
- DisGeNET
- Description
- To investigate the potential association between five cytokine promoter polymorphisms (interleukin [IL] 1b -511C→T [rs16944], IL-4 receptor [IL-4R] -3223C→T [rs2057768], IL-8 -251T→A [rs4073], IL-10 -1082A→G [rs1800896] and tumour necrosis factor-alpha -308G→A [rs1800629]) and susceptibility to gastric adenocarcinoma in a Romanian population.
- Pubmed
- 22891178
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.00453856695524446
- Year of publication
- 2012
Drugs